The Baylor team took a different approach by focusing on a protein called Sox9, a key regulator of gene activity in aging astrocytes. When they increased Sox9 levels in mice that had already developed memory problems and plaque buildup, the results were striking. Astrocytes became more active and began clearing the plaques.
https://scitechdaily.com/researchers-discover-boosting-a-single-protein-helps-the-brain-fight-alzheimers/