According to Wikipedia, the word "f-uck" is used 506 times over "The Wolf of Wall Street's" 180-minute running time. Previously, the record for a non-documentary was Spike Lee's 1999 film "Summer of Sam" with 435 instances.
File under: Important info from Nice MF
Neither of which equal the record for a Bill Gates software review.
http://www.joelonsoftware.com/items/2006/06/16.html - search on "F word"