Author Topic: Link between Alzheimer's disease and gut microbiota is confirmed  (Read 1031 times)

rcjordan

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ergophobe

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Re: Link between Alzheimer's disease and gut microbiota is confirmed
« Reply #1 on: November 14, 2020, 05:54:45 PM »
Fascinating and also frustrating. We're still far from knowing the causes and effects along that chain.

I think if you are under 30, Alzheimer's is likely to be a solved problem in your lifetime. If you are between 50 and 80, most therapies will come along too late. If you're over 75, well, it's either already a problem or is coming slowly and late enough that you'll probably not suffer the worst of it. The bad cases I have known, all had major issues by age 70.

rcjordan

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Re: Link between Alzheimer's disease and gut microbiota is confirmed
« Reply #2 on: November 14, 2020, 08:26:33 PM »
I think gingivitis or possibly other periodontal bacteria are part of the puzzle.  IIRC, other articles I've read say gingivitis was found to penetrate the supposedly impenetrable blood/brain barrier.

"found a modest link between severe gum disease and dementia, which is consistent with some previous studies."

Study links severe gum disease to raised dementia risk
https://www.medicalnewstoday.com/articles/324760
 

ergophobe

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Re: Link between Alzheimer's disease and gut microbiota is confirmed
« Reply #3 on: June 04, 2021, 07:43:58 PM »
This is fascinating....

EARLY TRIAL SHOWS FLICKERING LIGHTS COULD FIGHT ALZHEIMERíS
https://www.futurity.org/flickering-lights-sound-alzheimers-disease-2575812-2

TL;DR - flickering lights with a synchronized sound pulse at 40Hz results in "entrainment," that is, pulling the brain waves into the same rhythm, which is the gamma wave frequency, which is the state in which the brain cleans up and does housekeeping.

ergophobe

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Re: Link between Alzheimer's disease and gut microbiota is confirmed
« Reply #4 on: June 09, 2021, 11:10:26 PM »
Meanwhile, the Biogen drug shown to reduce amyloid plaque but not yet shown to reduce symptoms of Alzheimer's has FDA approval
https://www.economist.com/science-and-technology/2021/06/07/americas-wary-approval-of-an-alzheimers-drug-offers-hope-to-millions

rcjordan

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Re: Link between Alzheimer's disease and gut microbiota is confirmed
« Reply #5 on: June 09, 2021, 11:44:46 PM »
>Biogen drug

All I can figure is that there's a payoff in there somewhere.  At $56k per patient per year, it won't take long.

rcjordan

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Re: Link between Alzheimer's disease and gut microbiota is confirmed
« Reply #6 on: June 10, 2021, 03:58:32 PM »
>payoff (rc's conspiracy theory)

2 FDA committee members resign over Biogen Alzheimer's drug approval | Fox News
https://www.foxnews.com/health/2-fda-committee-members-resign-biogen-alzheimers-drug-approval

rcjordan

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Re: Link between Alzheimer's disease and gut microbiota is confirmed
« Reply #7 on: June 10, 2021, 11:19:21 PM »
+

Third member of prestigious FDA panel resigns over approval of Biogen's Alzheimer's drug

https://www.cnbc.com/amp/2021/06/10/third-member-of-prestigious-fda-panel-resigns-over-approval-of-biogens-alzheimers-drug.html

ergophobe

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ergophobe

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Re: Link between Alzheimer's disease and gut microbiota is confirmed
« Reply #9 on: June 16, 2021, 08:21:19 PM »
All I can figure is that there's a payoff in there somewhere.  At $56k per patient per year, it won't take long.

The new Alzheimerís drug that could break Medicare
Patients are desperate for hope. But there are serious concerns about Biogenís new $56,000 treatment.
https://www.vox.com/policy-and-politics/22524608/new-alzheimers-drug-cost-fda-approval-biogen

rcjordan

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Re: Link between Alzheimer's disease and gut microbiota is confirmed
« Reply #10 on: June 17, 2021, 12:33:08 AM »
I read somewhere that Medicare co-pay is likely to be $12k / year.


Biogen's debated Alzheimer's drug given to first patient

https://www.foxnews.com/health/biogen-alzheimers-drug-first-patient-rhode-island-man