Tim Ferriss always talks about making the one decision that avoids a hundred downstream decisions.
Having made a handful of political donations and having given my email address to various politicians when contacting them on issues, it seems that they share it like crazy. So years ago I made a decision to never donate to anyone who calls on the phone, since that's the most disruptive. That makes it easy to field calls.
But I still get email pitches from all sorts of politicians who do not represent me, most of whom I have never heard of. I have a new simple rule - any email that comes from someone for whom I am not a potential constituent, immediately gets unsubscribed. No figuring out whether or not I support their cause or oppose it.
And as a secondary thing, if it is not a one-click unsubscribe (like they make me fill in my email address in order to unsubscribe), then it gets marked as spam, even if I wholeheartedly support their agenda.
I've finally gotten to the point where I get few such messages and most of those go straight to the spam folder.