I tried for a while, but it didn't work for my business model.
I was applying the same techniques as worked well for my ebay aff stuff - quick and dirty sites relying on long tail searches. Amazon didn't have enough variety in the inventory for this to work well, plus what little traffic I sent them paid far less than ebay did.
I know some guys through one of the ebay related aff forums who claim to have made it work, they said it needed a different business model with more presell and a better quality site. I have no way of knowing if they were telling the truth though.